For today’s paper, I wrote about late blight – you may know it better as potato blight, the disease that caused the Irish Potato Famine. It’s still a huge problem for potato and tomato farmers, so a bunch of scientists sequenced its genome (their paper is in Nature today). Here’s my story.

Usually when I read about some new genome sequence, I get a big “eh” feeling. As in, “eh, big string of As, Gs, Cs, and Ts, who cares.” But this is a really cool disease, and super important economically, and it turns out the genome itself is interesting, too.

The organism that causes late blight has a ginormous genome, with a ton of repeating sequences of DNA. Those big repeaty areas include lots of copies of the nasty genes that help it attack plants, like genes that cause cell death and stuff. So maybe there’s some way that the bug is using those extra copies to overcome the plants’ defenses. Cool, huh?

Chad Nussbaum, the guy at the Broad Institute whose group did the sequencing, said this genome was really hard because of all the repeats – and it helped them figure out stuff they can use later. “Every genome teaches you something new,” he told me. “They’re all strange in their own little ways.”

Best thing I found while working on this story: PotatoPro, a news source for the potato processing industry with headlines like “Sultry Sally has re-launched its low fat potato chip with even less fat” and “Man dies after falling into potato harvester.”